Should Automatic Windows updates be disabled

Agreed. Windows has a nasty habit of wanting to restart after an update. You lose control over the process.

Not saying to never update the system. But I suggest backups. Preferably with something like Acronis that you can automate.

Also, if everything is on the same machine (Ignition, db, other OPC Servers, etc.), I recommend putting the database data and Ignition backups on a physically separate drive. That way, if/when the system drive tanks-- for whatever reason-- you get to keep as much data as possible.